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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JMIR Human Factors</journal-id>
      <journal-id journal-id-type="nlm-ta">JMIR Hum Factors</journal-id>
      <journal-title>JMIR Human Factors</journal-title>
      <issn pub-type="epub">2292-9495</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v9i2e33706</article-id>
      <article-id pub-id-type="pmid">35471472</article-id>
      <article-id pub-id-type="doi">10.2196/33706</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Original Paper</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Original Paper</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Adoption of a Postoperative Pain Self-Report Tool: Qualitative Study</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Kushniruk</surname>
            <given-names>Andre</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Mohseni</surname>
            <given-names>Ali Reza</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Chaudhry</surname>
            <given-names>Beenish</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author" corresp="yes" equal-contrib="yes">
          <name name-style="western">
            <surname>Thiel</surname>
            <given-names>Bram</given-names>
          </name>
          <degrees>MPA, MSc</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>Department of Anesthesiology</institution>
            <institution>OLVG Hospital</institution>
            <addr-line>Oosterpark 9</addr-line>
            <addr-line>Amsterdam, 1091AC</addr-line>
            <country>Netherlands</country>
            <phone>31 0205994773</phone>
            <email>b.thiel@olvg.nl</email>
          </address>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-5283-2173</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author" equal-contrib="yes">
          <name name-style="western">
            <surname>Iao</surname>
            <given-names>Inez</given-names>
          </name>
          <degrees>MSc</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-1711-8665</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author">
          <name name-style="western">
            <surname>Smid</surname>
            <given-names>Joris</given-names>
          </name>
          <degrees>MSc</degrees>
          <xref rid="aff3" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-5391-9868</ext-link>
        </contrib>
        <contrib id="contrib4" contrib-type="author">
          <name name-style="western">
            <surname>de Wit</surname>
            <given-names>Emmy</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff4" ref-type="aff">4</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-4047-0555</ext-link>
        </contrib>
        <contrib id="contrib5" contrib-type="author">
          <name name-style="western">
            <surname>Koopman</surname>
            <given-names>Seppe</given-names>
          </name>
          <degrees>MD, PhD</degrees>
          <xref rid="aff5" ref-type="aff">5</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-3704-8492</ext-link>
        </contrib>
        <contrib id="contrib6" contrib-type="author">
          <name name-style="western">
            <surname>Geerts</surname>
            <given-names>Bart</given-names>
          </name>
          <degrees>MD, MBA, PhD</degrees>
          <xref rid="aff6" ref-type="aff">6</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-0210-7202</ext-link>
        </contrib>
        <contrib id="contrib7" contrib-type="author">
          <name name-style="western">
            <surname>Godfried</surname>
            <given-names>Marc</given-names>
          </name>
          <degrees>MD, PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-7668-8185</ext-link>
        </contrib>
        <contrib id="contrib8" contrib-type="author">
          <name name-style="western">
            <surname>Kalkman</surname>
            <given-names>Cor</given-names>
          </name>
          <degrees>MD, PhD, Prof Dr</degrees>
          <xref rid="aff7" ref-type="aff">7</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-8372-6960</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>Department of Anesthesiology</institution>
        <institution>OLVG Hospital</institution>
        <addr-line>Amsterdam</addr-line>
        <country>Netherlands</country>
      </aff>
      <aff id="aff2">
        <label>2</label>
        <institution>Department of Services and Solutions Delivery</institution>
        <institution>Philips Benelux</institution>
        <addr-line>Amsterdam</addr-line>
        <country>Netherlands</country>
      </aff>
      <aff id="aff3">
        <label>3</label>
        <institution>Department of Cardiology</institution>
        <institution>OLVG Hospital</institution>
        <addr-line>Amsterdam</addr-line>
        <country>Netherlands</country>
      </aff>
      <aff id="aff4">
        <label>4</label>
        <institution>Faculty of Science</institution>
        <institution>Athena Institute</institution>
        <institution>Vu University</institution>
        <addr-line>Amsterdam</addr-line>
        <country>Netherlands</country>
      </aff>
      <aff id="aff5">
        <label>5</label>
        <institution>Department of Anesthesiology</institution>
        <institution>Maasstad Hospital</institution>
        <addr-line>Rotterdam</addr-line>
        <country>Netherlands</country>
      </aff>
      <aff id="aff6">
        <label>6</label>
        <institution>Department of Intensive Care</institution>
        <institution>Spaarne Gasthuis Hospital</institution>
        <addr-line>Haarlem</addr-line>
        <country>Netherlands</country>
      </aff>
      <aff id="aff7">
        <label>7</label>
        <institution>Department of Anesthesia and Intensive Care</institution>
        <institution>University Medical Centre Utrecht</institution>
        <addr-line>Utrecht</addr-line>
        <country>Netherlands</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Bram Thiel <email>b.thiel@olvg.nl</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <season>Apr-Jun</season>
        <year>2022</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>26</day>
        <month>4</month>
        <year>2022</year>
      </pub-date>
      <volume>9</volume>
      <issue>2</issue>
      <elocation-id>e33706</elocation-id>
      <history>
        <date date-type="received">
          <day>20</day>
          <month>9</month>
          <year>2021</year>
        </date>
        <date date-type="rev-request">
          <day>7</day>
          <month>12</month>
          <year>2021</year>
        </date>
        <date date-type="rev-recd">
          <day>13</day>
          <month>1</month>
          <year>2022</year>
        </date>
        <date date-type="accepted">
          <day>3</day>
          <month>2</month>
          <year>2022</year>
        </date>
      </history>
      <copyright-statement>©Bram Thiel, Inez Iao, Joris Smid, Emmy de Wit, Seppe Koopman, Bart Geerts, Marc Godfried, Cor Kalkman. Originally published in JMIR Human Factors (https://humanfactors.jmir.org), 26.04.2022.</copyright-statement>
      <copyright-year>2022</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Human Factors, is properly cited. The complete bibliographic information, a link to the original publication on https://humanfactors.jmir.org, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://humanfactors.jmir.org/2022/2/e33706" xlink:type="simple"/>
      <abstract>
        <sec sec-type="background">
          <title>Background</title>
          <p>With electronic technologies, patients are provided with tools to easily acquire information and to manage and record their own health status. eHealth interventions are already broadly applied to perioperative care. In a similar way, we aimed to utilize a smartphone application to enable postoperative patients to partially self-manage their postoperative pain. The results of a previously performed proof-of-concept study regarding the application were promising, and nurses as well as patients were optimistic regarding this innovative mobile application. Nevertheless, in reality, it appears that the usage and overall implementation of this application have stagnated since its introduction. Problems with innovation adoption are not novel; various studies have been conducted to explore the reasons for low implementation success of eHealth applications and indicated that adoption is influenced by multiple organizational factors. This study investigated the influence of these organizational factors on the adoption process, aiming to provide more insight in the dos and don’ts for implementing eHealth in the working processes of hospital care.</p>
        </sec>
        <sec sec-type="objective">
          <title>Objective</title>
          <p>This study aimed to provide insight in how to successfully implement a technological eHealth innovation in a general nonacademic hospital.</p>
        </sec>
        <sec sec-type="methods">
          <title>Methods</title>
          <p>A qualitative study was conducted to explore organizational factors affecting the innovation adoption process. Data were collected by conducting semistructured one-on-one interviews with 11 stakeholders. The data were analyzed using thematic analysis identifying overarching themes.</p>
        </sec>
        <sec sec-type="results">
          <title>Results</title>
          <p>Absorptive capacity, referred to as an organization’s dynamic capability pertaining to knowledge creation and utilization that enhances an organization’s ability to gain and sustain a competitive advantage, was regarded as the most influential factor on the application’s adoption. Accordingly, it appeared that innovation adoption is mainly determined by the capability and willingness to assimilate and transform new information into productive use and the ability to absorb a novel innovation. Absorptive capacity was found to be influenced by the innovation’s benefit and the sense of ownership and responsibility. Organizational readiness and management support were also regarded as essential since absorptive capacity seemed to be mediated by these factors. The size of the hospital influenced eHealth adoption by the amount of resources available and by its organizational structure.</p>
        </sec>
        <sec sec-type="conclusions">
          <title>Conclusions</title>
          <p>In conclusion, absorptive capacity is essential for eHealth adoption, and it is mediated by management support and organizational readiness. It is recommended to increase the degree of willingness and ability to adopt an eHealth innovation by enhancing the relevance, engaging stakeholders, and assigning appropriate leaders to offer guidance.</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>innovation</kwd>
        <kwd>eHealth adoption model, mobile health</kwd>
        <kwd>pain</kwd>
        <kwd>self-report</kwd>
        <kwd>perioperative medicine</kwd>
        <kwd>postoperative pain</kwd>
        <kwd>surgery</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <p>To date, hospital care, admission potential, urgent and nonurgent care, and health care professionals are under pressure due to problems such as the aging population, the rising prevalence of chronic comorbid diseases, and overall increasing health care costs [<xref ref-type="bibr" rid="ref1">1</xref>,<xref ref-type="bibr" rid="ref2">2</xref>]. On top of these already existing problems came the COVID-19 pandemic. These growing demands accelerate the surge in eHealth innovations [<xref ref-type="bibr" rid="ref3">3</xref>-<xref ref-type="bibr" rid="ref5">5</xref>].</p>
      <p>With electronic technologies, patients are provided with tools to easily acquire information and to manage and record their own health status. eHealth interventions are already broadly applied to perioperative care (eg, remote monitoring, educational websites, and telerehabilitation) [<xref ref-type="bibr" rid="ref6">6</xref>,<xref ref-type="bibr" rid="ref7">7</xref>]. In a similar way, we aimed to utilize an eHealth tool (the OLVG Pain App) with the objective to improve the efficiency and quality of postoperative pain management. This eHealth tool enables the patient to partially self-manage their postoperative pain, as they record their own postoperative pain intensity in their electronic medical record. The results of a previously performed proof-of-concept study regarding the OLVG Pain App were promising, and nurses as well as patients were optimistic regarding this innovative mobile application [<xref ref-type="bibr" rid="ref8">8</xref>].</p>
      <p>Nevertheless, in reality, it appears that the usage and overall implementation of this application have stagnated since its introduction. Problems with innovation adoption are not novel; various studies have been conducted to explore the reasons for low implementation success of eHealth applications and indicated that adoption is influenced by multiple organizational factors such as technological knowledge and skills, financial aspects, social and organizational support, and a lack of education and training [<xref ref-type="bibr" rid="ref9">9</xref>-<xref ref-type="bibr" rid="ref13">13</xref>]. Therefore, the aim of this study was to provide insight on how to successfully implement a technological eHealth innovation in a general nonacademic hospital. Accordingly, the research question was: “How can the adoption process of the PainApp be understood with regards to the organizational factors within a general hospital?”</p>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Study Design</title>
        <p>A qualitative study was conducted between March 1, 2020, and July 31, 2020. Stakeholders involved with the development and implementation process of the application were interviewed to provide an in-depth understanding of how the context of a general hospital can facilitate or hamper the adoption of eHealth. The study was conducted and is reported according to the CONSORT-EHEALTH (Consolidated Standards of Reporting Trials of Electronic and Mobile HEalth Applications and onLine TeleHealth) checklist (V.1.6.1) [<xref ref-type="bibr" rid="ref14">14</xref>], the consolidated criteria for reporting qualitative research (COREQ) [<xref ref-type="bibr" rid="ref15">15</xref>], and the “Qualitative research: standards, challenges, methodological guidelines” by Malterud [<xref ref-type="bibr" rid="ref16">16</xref>].</p>
      </sec>
      <sec>
        <title>Recruitment</title>
        <p>For this study, the perceptions of stakeholders active within the departments of Information Technology (IT), Electronic Medical Record (EMR), Anesthesiology, and Nursing Staff Convention from 2 hospitals were investigated. Both OLVG Hospital and Maasstad Hospital are general hospitals providing surgical care for 23,000 patients annually.</p>
        <p>The sample size was determined by the concept of “information power,” which depends on the relevance of the participants included [<xref ref-type="bibr" rid="ref17">17</xref>,<xref ref-type="bibr" rid="ref18">18</xref>]. Based on this premise and similar studies, 11 participants were considered satisfactory, as the selected participants were highly informative and significant actors in the innovation procedure (<xref ref-type="table" rid="table1">Table 1</xref>, participant characteristics). Participants from specific departments within the OLVG Hospital and Maasstad Hospital were provided by personal contacts from the supervisors of this study.</p>
        <table-wrap position="float" id="table1">
          <label>Table 1</label>
          <caption>
            <p>Participant characteristics.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="170"/>
            <col width="140"/>
            <col width="200"/>
            <col width="80"/>
            <col width="90"/>
            <col width="130"/>
            <col width="190"/>
            <thead>
              <tr valign="top">
                <td>Identification number</td>
                <td>Hospital</td>
                <td>Position</td>
                <td>Age (years)</td>
                <td>Gender</td>
                <td>Work experience (years)</td>
                <td>Technical background</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>P1</td>
                <td>OLVG Hospital</td>
                <td>Anesthetist</td>
                <td>52</td>
                <td>M<sup>a</sup></td>
                <td>17</td>
                <td>6 years of postoperative home monitoring and digitalized preoperative screening</td>
              </tr>
              <tr valign="top">
                <td>P2</td>
                <td>OLVG Hospital</td>
                <td>Nurse, application specialist</td>
                <td>42</td>
                <td>M</td>
                <td>18</td>
                <td>6 years as an application specialist for the EHR<sup>b</sup></td>
              </tr>
              <tr valign="top">
                <td>P3</td>
                <td>Maasstad Hospital</td>
                <td>Anesthetist</td>
                <td>39</td>
                <td>M</td>
                <td>6</td>
                <td>1 year as a CMIO<sup>c</sup></td>
              </tr>
              <tr valign="top">
                <td>P4</td>
                <td>OLVG Hospital</td>
                <td>Neurologist</td>
                <td>39</td>
                <td>M</td>
                <td>6</td>
                <td>3 years as an innovation specialist, human-centered design, and eHealth implementation</td>
              </tr>
              <tr valign="top">
                <td>P5 LKru</td>
                <td>OLVG Hospital</td>
                <td>Department manager</td>
                <td>45</td>
                <td>M</td>
                <td>10</td>
                <td>5 years as a manager of the EHR and patient participation</td>
              </tr>
              <tr valign="top">
                <td>P6</td>
                <td>OLVG Hospital</td>
                <td>Nurse team leader</td>
                <td>37</td>
                <td>F<sup>d</sup></td>
                <td>15</td>
                <td>3 years as a key user of the EPIC EHR</td>
              </tr>
              <tr valign="top">
                <td>P7</td>
                <td>OLVG Hospital</td>
                <td>Department manager</td>
                <td>-<sup>e</sup></td>
                <td>M</td>
                <td>-</td>
                <td>6 years as a manager of the ICT<sup>f</sup> department</td>
              </tr>
              <tr valign="top">
                <td>P8</td>
                <td>OLVG Hospital</td>
                <td>Nurse team leader</td>
                <td>-</td>
                <td>F</td>
                <td>28</td>
                <td>10 years as a nurse team leader in the neurosurgery department</td>
              </tr>
              <tr valign="top">
                <td>P9</td>
                <td>OLVG Hospital</td>
                <td>Operational manager</td>
                <td>-</td>
                <td>F</td>
                <td>39</td>
                <td>4 years as a manager of the neurosurgery business unit</td>
              </tr>
              <tr valign="top">
                <td>P10</td>
                <td>OLVG Hospital</td>
                <td>Pulmonologist</td>
                <td>62</td>
                <td>M</td>
                <td>30</td>
                <td>2 years as a CMIO</td>
              </tr>
              <tr valign="top">
                <td>P11</td>
                <td>Maasstad Hospital</td>
                <td>Clinical computer scientist</td>
                <td>34</td>
                <td>M</td>
                <td>5</td>
                <td>Specialty connectivity between medical devices and the EHR</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table1fn1">
              <p><sup>a</sup>M: male.</p>
            </fn>
            <fn id="table1fn2">
              <p><sup>b</sup>EHR: electronic health record.</p>
            </fn>
            <fn id="table1fn3">
              <p><sup>c</sup>CMIO: Chief Medical Information Officer.</p>
            </fn>
            <fn id="table1fn4">
              <p><sup>d</sup>F: female.</p>
            </fn>
            <fn id="table1fn5">
              <p><sup>e</sup>Participant did not respond to the extra questions for age and years of work experience.</p>
            </fn>
            <fn id="table1fn6">
              <p><sup>f</sup>ICT: information communication and technology.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
      </sec>
      <sec>
        <title>Data Collection</title>
        <p>The data were collected during semistructured one-on-one interviews performed by a research student (IK). The interviews were structured by the following topic questions: size of the hospital, top management support, organizational readiness, and centralization in decision-making and absorptive capacity. These topics were based on pre-established themes derived from the eHealth Adoption Model (eHAM) [<xref ref-type="bibr" rid="ref19">19</xref>]. The eHAM combines elements of the diffusion of innovation theory and the technology-organization-environment framework, since these form a theoretical base of innovation in various sectors [<xref ref-type="bibr" rid="ref20">20</xref>].</p>
        <p>The interviews were conducted in Dutch; the interview guide was originally formulated in Dutch, followed by a translation into English for the purpose of this report (<xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>). Prior to the interview, participants received some general information concerning the research topic, and informed consent was requested from the interviewee to allow for audio recording of the interview. The interview commenced with introductory questions, with which the general opinion on eHealth innovations of eeeof the participant was established. After this introductory phase, topic questions regarding the concepts of the eHAM model were asked to explore their experiences with and perspectives on the influences of these factors. Lastly, specific closing questions recapping the themes were asked to evaluate the importance of each organizational factor. Furthermore, interviews were conducted online through Skype, Zoom, or FaceTime due to COVID-19 measures.</p>
      </sec>
      <sec>
        <title>Data Analysis</title>
        <p>Data collection and analysis progression were discussed during regular meetings with the researchers BT and JS and the research student IK. A thematic framework approach was utilized in order to analyze the qualitative data [<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref22">22</xref>]. First, the audio recordings of the interviews were transcribed verbatim in Dutch. As for the validity, the interpretations of the interview were sent to the respective participants to check whether the interviews were well understood and in line with their perspectives. After familiarization with the data, the transcripts were coded with an English coding guide that was developed according to the eHAM model. The coding guide included the 5 main concepts regarding the organizational factors, which were further differentiated into subconcepts. After coding, overarching themes and patterns were identified and labelled within each concept.</p>
      </sec>
      <sec>
        <title>Ethics Approval</title>
        <p>This study was conducted as part of the “Closing the loop” project approved by the Advisory board for Science and Research (ACWO) OLVG Hospital on December 30, 2019, with registration number WO 19.167.</p>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <sec>
        <title>Themes</title>
        <p>The results were derived from stakeholder interviews and yielded a total of more than 40 themes that are related to the eHAM [<xref ref-type="bibr" rid="ref19">19</xref>]. For a visualized overview of all identified and related themes, see <xref ref-type="supplementary-material" rid="app2">Multimedia Appendix 2</xref>. Overall, the stakeholders considered absorptive capacity, top management support, and organizational readiness as the most essential factors for the adoption of eHealth innovation. For interview data, see <xref ref-type="supplementary-material" rid="app3">Multimedia Appendix 3</xref>. Moreover, the remaining 2 factors (ie, size of the hospital and centralization in decision-making) were considered as generic influences and are therefore briefly discussed.</p>
      </sec>
      <sec>
        <title>Absorptive Capacity</title>
        <p>Absorptive capacity appeared to be of great importance. Absorptive capacity refers to an organization’s “dynamic capability pertaining to knowledge creation and utilization that enhances an organization’s ability to gain and sustain a competitive advantage” [<xref ref-type="bibr" rid="ref23">23</xref>].</p>
        <p>The majority of stakeholders stated that the individual’s willingness is an essential aspect that can affect the degree of absorptive capacity. Next to the willingness to absorb new information, the ability to do so is also essential for successful innovation adoption.</p>
        <p>Altogether, the participants mentioned that spreading new knowledge is more effective when done repetitively face-to-face, than, for instance, digitally through newsletters or by email. Clinical lessons and pilot tests can also be used to effectively introduce innovations or increase the skills of employees.</p>
        <p>Another important aspect mentioned to influence absorptive capacity is the culture within the hospital, as a culture that is more “open” and stimulating in accepting new information can enhance the adaptability and flexibility of the organization.</p>
        <p>Furthermore, this willingness and ability to adopt certain innovations also appeared to depend on various themes, such as personal characteristics, the context, and whether a sense of ownership and responsibility is present with the individual. The influence of personal characteristics on absorptive capacity became evident as 9 of 11 participants noted that features such as age (or generation), affinity with technology, and being an early or late adopter can affect whether an individual absorbs an innovation. Accordingly, a team leader stated:</p>
        <disp-quote>
          <p>When talking about absorptive capacity, it also depends a lot on the type of person. How much information can you assimilate? Are you theoretical or more practical? How old are you? Do you have an affinity for innovation and technology?</p>
          <attrib>P6, team leader</attrib>
        </disp-quote>
        <p>Additionally, 6 (P9, P1, P4, P5, P3, P6) participants felt that hospital employees are commonly not very capable of acquiring, assimilating, transforming, and connecting new information to existing knowledge for productive use. They believed that hospital employees are extremely programmed to conform to protocols, which limits the potential for adoption and particularly affects their ability to embed innovations into practiced daily routines. An essential remark made by all participants is that the context in which the innovation adoption takes place has a significant role in whether individuals are willing to absorb it. It became clear that the severity or urgency of the problem that the innovation addresses and responds to should be sufficiently experienced by those who need to use the innovation.</p>
        <p>In addition, all participants mentioned that the innovation’s relevance is a key factor for successful innovation adoption and that this mainly depends on whether there is a substantial benefit to fulfill the need of the user. Another theme that emerged from 6 interviews was that the innovation should induce a sense of ownership in order for employees to truly adopt the eHealth innovation.</p>
      </sec>
      <sec>
        <title>Top Management Support</title>
        <p>Next to the absorptive capacity, the support of top management also appears to be of great influence, as managers are recognized to be responsible for delivering the required resources to facilitate innovation adoption. An anesthetist described the top management’s influence accordingly:</p>
        <disp-quote>
          <p>I think they certainly have an impact. They have to provide the money to be able to introduce eHealth tools such as the OLVG Pain app and support ICT and so on. Thus, if they say we won’t be doing it, then it won’t happen.</p>
          <attrib>P3, anesthetist</attrib>
        </disp-quote>
        <p>In addition, top management also seems to be responsible for arranging employees and project structures for realization. All participants agree that commitment from the top and a supportive vision of innovations should be present for successful eHealth adoption. More importantly, one of the team leaders stated that all management layers should be committed, in particular the team leaders, since they are practically active at the site of implementation:</p>
        <disp-quote>
          <p>You want it to be implemented in the workplace, so you should focus on there. The employees have no idea of what is happening in the top of the organization. If it is transmitted by a team leader, then they will believe and follow it.</p>
          <attrib>P8, team leader</attrib>
        </disp-quote>
      </sec>
      <sec>
        <title>Organizational Readiness</title>
        <p>Most of the participants experienced that the actual IT infrastructure was adequately present to facilitate technological developments. However, P6 did mention that the hospitals lag behind some current technologies due to limited financial resources and complex privacy concerns:</p>
        <disp-quote>
          <p>For example, we still do not have a blood pressure meter that automatically sends the data into the patient data management system (PDMS) via Wi-Fi. Nowadays, it must be possible to automatically Bluetooth or Wi-Fi everything to the system; why is it not possible for us to realize this?</p>
          <attrib>P6, team leader</attrib>
        </disp-quote>
        <p>Some participants supported this decision as they believed that hospitals are not supposed to compete with third-party app developers:</p>
        <disp-quote>
          <p>I don't think we'll be any better at it, because the hospital is good at treating patients and our core business is not building an app.</p>
          <attrib>P5, department manager</attrib>
        </disp-quote>
      </sec>
      <sec>
        <title>Financial Readiness</title>
        <p>The majority of participants mentioned that they are aware that hospitals have relatively little financial resources. Furthermore, most of the participants recognized that the financial readiness for eHealth innovations mainly depends on the innovation’s significance and potential for success. P6 described this accordingly:</p>
        <disp-quote>
          <p>Yes, if an innovation doctor says: “Yes we have to do this and I know it costs 100 thousand euros,” the innovation committee can still object by saying that there is no money for that, because it has to be spent on new patient beds, as that is simply more important than that innovation.</p>
          <attrib>P6, team leader</attrib>
        </disp-quote>
      </sec>
      <sec>
        <title>Size of the Hospital</title>
        <p>Most of the participants agreed that the size of the hospital’s influence on eHealth implementation is associated with the available resources and the organizational structure. For instance, an IT employee mentioned that a larger hospital allows for more available resources, which in turn increases the organizational readiness for the adoption of eHealth innovations. On the other hand, a larger hospital appears to have more management layers and is therefore considered to be more bureaucratic in its structure. One of the participants (P5) stated correspondingly:</p>
        <disp-quote>
          <p>So yes, you have resources, but then again you are so big and bureaucratic that the speed of implementing innovations really slows down.</p>
          <attrib>P5, department manager</attrib>
        </disp-quote>
      </sec>
      <sec>
        <title>Centralization in Decision-making</title>
        <p>All participants agreed that centralization is required for a structured overview to focus on hospital-wide interests and a fairer selection procedure of all projects. P5 described that a centralized group can positively influence eHealth adoption by providing guidance and resources:</p>
        <disp-quote>
          <p>That central group helps with getting a sharp picture of whether the innovation really matters and if that is what we want, and then they’ll help bridge the connection with those who can support, build, implement, and train it.</p>
          <attrib>P5, department manager</attrib>
        </disp-quote>
      </sec>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <sec>
        <title>Principal Findings</title>
        <p>The results of this study demonstrate that absorptive capacity is regarded as the most important factor influencing eHealth adoption in a general hospital. In addition, the degree of absorptive capacity is predominantly mediated by the amount of management support and the organizational readiness (<xref rid="figure1" ref-type="fig">Figure 1</xref>). However, the size of the hospital and centralization in decision-making are rather generic influences on the innovation process. Previous studies show supportive findings regarding the importance of absorptive capacity in influencing eHealth adoption [<xref ref-type="bibr" rid="ref24">24</xref>-<xref ref-type="bibr" rid="ref27">27</xref>]. We found that “being attached to follow fixed guidelines” (ie, working by following strict protocols), “context” (ie, the way urgency and relevance of a specific issue push an innovation), and the absence of a sense of ownership and responsibility affected absorptive capacity. Being a “family owner” could contribute to the willingness for innovation and therefore could positively influence absorptive capacity [<xref ref-type="bibr" rid="ref28">28</xref>]. Next to highlighting the importance of absorptive capacity itself, we also reveal that both management support and organizational readiness mediate this factor. Numerous other studies also present that absorptive capacity is influenced by organizational structure, culture, and communication [<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref29">29</xref>-<xref ref-type="bibr" rid="ref31">31</xref>].</p>
        <p>Our findings regarding organizational readiness are in accordance with other studies suggesting that organizations with a favorable environment, the structure, and the required resources are more prone to absorb innovations [<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref33">33</xref>].</p>
        <p>For financial readiness, we found that a hospital’s limited budget could be a barrier but would not be a determinant of the innovation’s actual success. It seemed that, rather, the innovation’s importance and potential to truly improve the quality of care would eventually determine the availability of financial resources.</p>
        <p>The size of the hospital was found to influence the innovation process, as a larger size is positively associated with a greater amount of organizational resources, which in turn can facilitate better innovation implementation. This is in line with previous literature indicating that a greater hospital size influences the likelihood of successful adoption [<xref ref-type="bibr" rid="ref34">34</xref>]. In contrast to this, our findings suggest that a greater size could also lead to a more bureaucratic structure and therefore even hamper innovation adoption despite its possession of more resources.</p>
        <p>As for the centralization of decision-making, it became clear that this organizational factor differed in influence depending on the specific stage of the innovation process. Despite the potential positive influence of an acknowledgeable centralized group in guiding the innovation implementation, the stakeholders in our study ranked this factor as one of the least influential for successful adoption.</p>
        <fig id="figure1" position="float">
          <label>Figure 1</label>
          <caption>
            <p>Absorptive capacity in relation to mediating factors.</p>
          </caption>
          <graphic xlink:href="humanfactors_v9i2e33706_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
      </sec>
      <sec>
        <title>Limitations</title>
        <p>This study has several limitations; despite the recruitment of stakeholders from 2 different hospitals, the results and key messages of this study are mainly valid for the OLVG specifically, as the great majority of interviewees came from this hospital. This might have limited the acquirement of in-depth details on certain factors. The use of a conceptual model enabled this study to provide more insights into how the organizational factors influence adoption and to structure an overview of how these different factors relate to each other in terms of prioritization. However, the inclusion of such an extensive number of organizational factors may also have hampered a deeper understanding and exploration of each factor’s influence on its own. Accordingly, this is also the reason why the hospital’s “communication structures” have only been addressed briefly in our study and hence, lacks thoroughness in the findings.</p>
      </sec>
      <sec>
        <title>Recommendations for Practice</title>
        <p>The results revealed that adoption was prominently lacking on the innovation’s benefit and on the sense of ownership and responsibility, which in turn negatively affected the absorptive capacity. Therefore, we suggest 3 focal points for policy.</p>
        <p>The first focal point follows the “Quadruple Aim criteria” as a concept that focuses on examining the innovation according to the following 4 aims: lower cost of care, improved patient care, better health outcomes, and improved staff experience [<xref ref-type="bibr" rid="ref35">35</xref>].</p>
        <p>The second focal point increases the absorptive capacity from various aspects by using the value-sensitive design approach to engage all stakeholders from the beginning, creating a sense of ownership and responsibility [<xref ref-type="bibr" rid="ref36">36</xref>].</p>
        <p>The third focal point relates to our finding that management has a major influence on organizational culture and thus, also on the absorptive capacity. Accordingly, appropriate leaders who are truly able to stimulate an innovation-friendly learning culture should engage stakeholders. Therefore, the allocation of ambassadors or managers can support in overcoming resistance to change concerning stakeholder engagement and creating the innovation’s benefit.</p>
      </sec>
      <sec>
        <title>Conclusions</title>
        <p>This study provides insight in how to successfully implement an eHealth innovation in a general hospital. The most important factor influencing eHealth adoption was absorptive capacity, which was mainly determined by the innovation’s urgency and relevance, and a sense of ownership and responsibility. Additionally, we revealed that absorptive capacity is mediated by management support and organizational readiness. Three focal points for successful eHealth adoption are enhancing the innovation’s relevance, adequately engaging stakeholders from the start, and allocating ambassadors or managers to support stakeholder engagement and to offer proper guidance and training.</p>
      </sec>
    </sec>
  </body>
  <back>
    <app-group>
      <supplementary-material id="app1">
        <label>Multimedia Appendix 1</label>
        <p>Interview guide.</p>
        <media xlink:href="humanfactors_v9i2e33706_app1.docx" xlink:title="DOCX File , 21 KB"/>
      </supplementary-material>
      <supplementary-material id="app2">
        <label>Multimedia Appendix 2</label>
        <p>Overview of the identified themes.</p>
        <media xlink:href="humanfactors_v9i2e33706_app2.png" xlink:title="PNG File , 120 KB"/>
      </supplementary-material>
      <supplementary-material id="app3">
        <label>Multimedia Appendix 3</label>
        <p>Interview data.</p>
        <media xlink:href="humanfactors_v9i2e33706_app3.xlsx" xlink:title="XLSX File  (Microsoft Excel File), 95 KB"/>
      </supplementary-material>
    </app-group>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">ACWO</term>
          <def>
            <p>Advisory board for Science and Research</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">CONSORT-EHEALTH</term>
          <def>
            <p>Consolidated Standards of Reporting Trials of Electronic and Mobile HEalth Applications and onLine TeleHealth</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">COREQ</term>
          <def>
            <p>consolidated criteria for reporting qualitative research</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb4">eHAM</term>
          <def>
            <p>eHealth adoption model</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb5">EMR</term>
          <def>
            <p>electronic medical record</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb6">IT</term>
          <def>
            <p>information technology</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb7">PDMS</term>
          <def>
            <p>patient data management system</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>This study was established from the internship in Master Management, Policy-analysis and entrepreneurship in Health and Life Science of II at OLVG Hospital, Course code: AM_1120. The internship was conducted as part of the Closing the Loop study approved by the local medical ethics committee and board of OLVG (WO 19.167). Researchers II and BT contributed equally to the final version of this manuscript.</p>
    </ack>
    <fn-group>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
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