TY - JOUR AU - Katzburg, Omer AU - Roimi, Michael AU - Frenkel, Amit AU - Ilan, Roy AU - Bitan, Yuval PY - 2024 DA - 2024/8/1 TI - The Impact of Information Relevancy and Interactivity on Intensivists’ Trust in a Machine Learning–Based Bacteremia Prediction System: Simulation Study JO - JMIR Hum Factors SP - e56924 VL - 11 KW - user-interface design KW - user-interface designs KW - user interface KW - human-automation interaction KW - human-automation interactions KW - trust in automation KW - automation KW - human-computer interaction KW - human-computer interactions KW - human-ML KW - human-ML interaction KW - human-ML interactions KW - decision making KW - decision support system KW - clinical decision support KW - decision support KW - decision support systems KW - machine learning KW - ML KW - artificial intelligence KW - AI KW - machine learning algorithm KW - machine learning algorithms KW - digitization KW - digitization of information AB - Background: The exponential growth in computing power and the increasing digitization of information have substantially advanced the machine learning (ML) research field. However, ML algorithms are often considered “black boxes,” and this fosters distrust. In medical domains, in which mistakes can result in fatal outcomes, practitioners may be especially reluctant to trust ML algorithms. Objective: The aim of this study is to explore the effect of user-interface design features on intensivists’ trust in an ML-based clinical decision support system. Methods: A total of 47 physicians from critical care specialties were presented with 3 patient cases of bacteremia in the setting of an ML-based simulation system. Three conditions of the simulation were tested according to combinations of information relevancy and interactivity. Participants’ trust in the system was assessed by their agreement with the system’s prediction and a postexperiment questionnaire. Linear regression models were applied to measure the effects. Results: Participants’ agreement with the system’s prediction did not differ according to the experimental conditions. However, in the postexperiment questionnaire, higher information relevancy ratings and interactivity ratings were associated with higher perceived trust in the system (P<.001 for both). The explicit visual presentation of the features of the ML algorithm on the user interface resulted in lower trust among the participants (P=.05). Conclusions: Information relevancy and interactivity features should be considered in the design of the user interface of ML-based clinical decision support systems to enhance intensivists’ trust. This study sheds light on the connection between information relevancy, interactivity, and trust in human-ML interaction, specifically in the intensive care unit environment. SN - 2292-9495 UR - https://humanfactors.jmir.org/2024/1/e56924 UR - https://doi.org/10.2196/56924 DO - 10.2196/56924 ID - info:doi/10.2196/56924 ER -