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The Comprehensive Adaptive Multisite Prevention of University Student Suicide Trial: Protocol for a Randomized Controlled Trial

The Comprehensive Adaptive Multisite Prevention of University Student Suicide Trial: Protocol for a Randomized Controlled Trial

The primary goal of aim 1 is to identify the most effective ATS among the 4 embedded strategies (A+B, A+C, D+E, or D+F, as shown in Table 2) that leads to the greatest reduction in STB. This aim focuses on finding the best-performing ATS rather than testing a hypothesis. The sample size of 480 was found to ensure an 80% probability of correctly identifying the ATS with the lowest mean outcome, assuming that such a strategy exists.

Kyla Blalock, Jacqueline Pistorello, Shireen L Rizvi, John R Seeley, Francesca Kassing, James Sinclair, Linda A Oshin, Robert J Gallop, Cassidy M Fry, Ted Snyderman, David A Jobes, Jennifer Crumlish, Hannah R Krall, Susan Stadelman, Filiz Gözenman-Sapin, Kate Davies, David Steele, David B Goldston, Scott N Compton

JMIR Res Protoc 2025;14:e68441