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Virtual Patients Using Large Language Models: Scalable, Contextualized Simulation of Clinician-Patient Dialogue With Feedback

Virtual Patients Using Large Language Models: Scalable, Contextualized Simulation of Clinician-Patient Dialogue With Feedback

To instantiate a specific VP, the interface accesses a 1-page case description. Narrative S1 in Multimedia Appendix 1 reports the full prompt and 1 case description. We selected as topics 2 common problems in ambulatory medicine: chronic cough (a diagnostic task) and diabetes (a management task). For each topic, we created a written description of a prototypical scenario. In this pilot study we did not base scenarios on specific real patients.

David A Cook, Joshua Overgaard, V Shane Pankratz, Guilherme Del Fiol, Chris A Aakre

J Med Internet Res 2025;27:e68486