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Assessment and Intervention for Diabetes Distress in Primary Care Using Clinical and Technological Interventions: Protocol for a Single-Arm Pilot Trial

Marisa Kostiuk, Susan L Moore, E Seth Kramer, Joshua Felton Gilens, Ashwin Sarwal, David Saxon, John F Thomas, Tamara K Oser

JMIR Res Protoc 2025;14:e62916

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Development of a Framework for Youth- and Family-Specific Engagement in Research: Proposal for a Scoping Review and Qualitative Descriptive Study

Sarah E P Munce, Clementine Jarrett, Vjura Senthilnathan, Dorothy Luong, Brooke Allemang, Katherine Bailey, Elaine Biddiss, Maria T Britto, Francine Buchanan, Christine Cassidy, Andrea Cross, Jessie Cunningham, Gina Dimitropoulos, Scott E Hadland, Monika Kastner, Tieghan Killackey, Kristina Kokorelias, Colin Macarthur, Samantha Micsinszki, Chavon Niles, F Virginia Wright, Alene Toulany

JMIR Res Protoc 2025;14:e65733

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Unintended Prolonged Opioid Use: Protocol for a Case-Controlled Trial

W Michael Hooten, Darin J Erickson, Marek Chawarski, Natalie A Scholz, Jennifer F Waljee, Chad M Brummett, Molly M Jeffery

JMIR Res Protoc 2025;14:e72032

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A Technology System to Help People With Multiple Disabilities Increase Contact With Objects and Control Environmental Stimulation: Single-Case Research Design

The study complied with the 1964 Helsinki Declaration and its later amendments and was approved by the Ethics Committee of the Lega F. D’Oro, Osimo (AN), Italy (P030820241). Figures 2 reports the data for Liam, Hallie, Logan, and Kali and Figure 3 reports the data for Harper, Jacob, Millie, and Isabel over the different phases of the study. Each data point represents the mean frequency of responses per session over a block (group) of sessions.

Giulio E Lancioni, Gloria Alberti, Chiara Filippini, Nirbhay N Singh, Mark F O'Reilly, Jeff Sigafoos, Valeria Chiariello, Oriana Troccoli

JMIR Rehabil Assist Technol 2025;12:e70378

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Developing and Implementing Provider-Training and Evidence-Based Tools to Support Pre-exposure Prophylaxis (PrEP) Decision-Making and Increase PrEP Adherence Among Young Men Who Have Sex With Men: Protocol for the PrEP Choice Longitudinal Cohort Study

The US Food and Drug Administration has approved the use of 3 antiretroviral drugs for Pr EP by MSM: oral emtricitabine and tenofovir disoproxil fumarate (F/TDF) in 2012, followed by the availability of generic F/TDF in 2021; oral emtricitabine and tenofovir alafenamide (F/TAF) in 2018; and long-acting injectable cabotegravir (CAB-LA) in 2021. Clinical trials of sexual event-driven Pr EP regimens or 2-1-1 Pr EP using F/TDF have demonstrated it to be highly effective for HIV prevention among MSM [3,4].

Crissi Rainer, Rebecca Schnall, Mary R Tanner, Carla A Galindo, Karen W Hoover, Sylvie Naar, Maeve Brin, Andres Martinez, Haomiao Jia, Maria Mendoza, Lisa Hightow-Weidman