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Complete Blood Count and Monocyte Distribution Width–Based Machine Learning Algorithms for Sepsis Detection: Multicentric Development and External Validation Study

Complete Blood Count and Monocyte Distribution Width–Based Machine Learning Algorithms for Sepsis Detection: Multicentric Development and External Validation Study

The OGSA-ICU data refer to patients who were admitted to the ICU of the Istituto di Ricovero e Cura a Carattere Scientifico Ospedale Galeazzi Sant’Ambrogio between January 1, 2023 and April 31, 2023. The inclusion criteria were adult (aged ≥18 years) patients who were hospitalized in the ICU for at least 2 days (to exclude patients who were temporarily admitted to the ICU because of specific intervention protocols) and for whom blood culture and procalcitonin were requested.

Andrea Campagner, Luisa Agnello, Anna Carobene, Andrea Padoan, Fabio Del Ben, Massimo Locatelli, Mario Plebani, Agostino Ognibene, Maria Lorubbio, Elena De Vecchi, Andrea Cortegiani, Elisa Piva, Donatella Poz, Francesco Curcio, Federico Cabitza, Marcello Ciaccio

J Med Internet Res 2025;27:e55492