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Examining Weight Suppression, Leptin Levels, Glucagon-Like Peptide 1 Response, and Reward-Related Constructs in Severity and Maintenance of Bulimic Syndromes: Protocol and Sample Characteristics for a Cross-Sectional and Longitudinal Study

Examining Weight Suppression, Leptin Levels, Glucagon-Like Peptide 1 Response, and Reward-Related Constructs in Severity and Maintenance of Bulimic Syndromes: Protocol and Sample Characteristics for a Cross-Sectional and Longitudinal Study

Then, participants consumed a fixed liquid meal (Ensure Plus, Abbott Nutrition; 900 kcal in 660 g of fluid: 30% fat, 15% protein, and 55% carbohydrate) from –5 to 0 minutes. To capture GLP-1 and insulin responses to the fixed meal, 2 ml blood samples were drawn at +5, +15, and +30 minutes. Momentary ratings were completed immediately before each blood draw.

Pamela K Keel, Lindsay P Bodell, Sarrah I Ali, Austin Starkey, Jenna Trotta, J Woody Luxama, Chloé Halfhide, Naomi G Hill, Jonathan Appelbaum, Diana L Williams

JMIR Res Protoc 2025;14:e66554

Cooperative Virtual Reality Gaming for Anxiety and Pain Reduction in Pediatric Patients and Their Caregivers During Painful Medical Procedures: Protocol for a Randomized Controlled Trial

Cooperative Virtual Reality Gaming for Anxiety and Pain Reduction in Pediatric Patients and Their Caregivers During Painful Medical Procedures: Protocol for a Randomized Controlled Trial

The ethics committees of the other study centers, Universitätsklinikum Hamburg-Eppendorf, Germany, Ethik-Kommission der Ärztekammer Hamburg (approval 2023-200739-BO-bet) and Ethikkommission des Universitätsklinikum Schleswig-Holstein, Lübeck, Germany (approval 2023-708), also saw no ethical or legal objections to this study. All patients and caregivers will be fully informed about the background and procedure of the study during the recruitment process before they consent to participate in the study.

Stefan Liszio, Franziska Bäuerlein, Jens Hildebrand, Carolin van Nahl, Maic Masuch, Oliver Basu

JMIR Res Protoc 2025;14:e63098