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Skip search results from other journals and go to results- 3 Journal of Medical Internet Research
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Chronic kidney disease (CKD) is a common comorbidity of type 2 diabetes mellitus (T2 DM), which is a leading cause of death and disability worldwide [1-8]. Patients with CKD show persistently decreased estimated glomerular filtration rates (e GFRs) or persistently elevated urine albumin excretion [9-11], which may progress to end-stage renal disease [12]. A high-normal urine albumin-to-creatinine ratio (UACR) is associated with a significantly increased risk of all-cause mortality [13].
JMIR Form Res 2025;9:e60246
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Chronic kidney disease (CKD) is rapidly becoming a widespread noncommunicable chronic disease worldwide, presenting a significant public health challenge. It affects approximately 11%-13% of the global population. It is associated with a high mortality rate, substantial health care costs, particularly in its advanced stages, and a potential need for renal replacement therapy [1-4]. It is projected that by the year 2040, CKD will become the fifth leading cause of years of life lost globally [5].
J Med Internet Res 2024;26:e54206
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The 2011‐12 Australian Health Survey revealed that 10% of Australian adults had biochemical signs of chronic kidney disease (CKD) [1]. CKD is a significant risk factor for cardiovascular disease [2], which is Australia’s leading cause of death [3]. Early intervention can slow the deterioration in kidney function and reduce the risk of cardiovascular complications [4].
JMIR Hum Factors 2024;11:e55667
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Epidemiological research indicates that the prevalence of CKD in China stands at 10.8%, yet only 12.5% of impacted individuals are aware of their condition [40]. The early detection of CKD relies on nonnephrology clinicians; however, it is particularly challenging because early-stage CKD often exhibits fewer symptoms. However, insufficient CKD knowledge among nonnephrology clinicians may result in the oversight of CKD-related risks during routine practice.
J Med Internet Res 2024;26:e54263
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Chronic kidney disease (CKD) affects up to 50% of all patients with type 2 diabetes mellitus (DM2) [4,5] and is common in patients without diabetes as well. It ranks just below diabetes as the 10th leading global cause of death, resulting in an estimated 1.3 million deaths annually. The most common cause of death in both patients with diabetes and patients with CKD is CVD [3,6].
Recently, sodium-glucose-cotransporter 2 (SGLT) inhibitors (SGLT2is) have revolutionized the treatment of both DM2 and CKD.
JMIR Res Protoc 2024;13:e56067
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With this in mind, the Smit-CKD project aimed at developing an integrated system designed for general practitioners (GPs) and patients consisting of a web-based platform (Smit-CKD server) and an app (Smit-CKD app), with the aim of improving medication regimen compliance and educating patients in self-monitoring of the most common risk factors for CKD and cardiovascular disease.
JMIR Bioinform Biotech 2022;3(1):e36766
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However, as many as half of patients with advanced CKD are unaware that they have kidney disease, including those at high risk for kidney function decline [3] and those with laboratory manifestations of their kidney disease [4,5].
Reasons for the low prevalence of CKD awareness among individuals with CKD are varied and include patient, provider, and health system factors [6].
JMIR Form Res 2022;6(9):e40001
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CKD: chronic kidney disease; e GFR: estimated glomerular filtration rate; DM: diabetes; HTN: hypertension; u ACR: urine albumin-creatinine ratio.
Clinician-identified barriers and enablers for optimal discussions about chronic kidney disease informed the creation of the Kidney Score Platform’s Clinical Practice Toolkit.
JMIR Res Protoc 2020;9(10):e22024
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The nephrology community recognizes the need to monitor PROs in chronic kidney disease (CKD) care [2,3]. Areas of emphasis to date include assessing dialysis patients’ physical and mental impairment [4], preferences and experiences with renal replacement therapy [5,6], and the symptom burden of CKD-related anemia [7].
J Med Internet Res 2016;18(5):e125
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