Published on in Vol 13 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/75465, first published .
Wearable Device Photoplethysmography As a Viable Tool to Longitudinally Monitor Vasoconstriction Biomarkers for Predicting Vaso-Occlusive Crisis in Sickle Cell Disease: Feasibility and Validation Study

Wearable Device Photoplethysmography As a Viable Tool to Longitudinally Monitor Vasoconstriction Biomarkers for Predicting Vaso-Occlusive Crisis in Sickle Cell Disease: Feasibility and Validation Study

Wearable Device Photoplethysmography As a Viable Tool to Longitudinally Monitor Vasoconstriction Biomarkers for Predicting Vaso-Occlusive Crisis in Sickle Cell Disease: Feasibility and Validation Study

Payal Shah   1 , MS ;   Sabrina Sy   2 , BS ;   Mingjing Chen   2 , BS ;   Michael CK Khoo   2 , PhD ;   Thomas D Coates   1 , MD ;   Saranya Veluswamy   1 , MD

1 Division of Hematology, Cancer and Blood Disease Institute, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA, United States

2 Alfred E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, United States

Corresponding Author:

  • Saranya Veluswamy, MD
  • Division of Hematology, Cancer and Blood Disease Institute
  • Children's Hospital Los Angeles, University of Southern California
  • 4650 Sunset Boulevard
  • Los Angeles, CA 90027
  • United States
  • Phone: 1 3233615507
  • Email: sveluswamy@chla.usc.edu