This paper is in the following e-collection/theme issue:

Psychological, Behavioral, Social, and/or Cultural Experiments and Interventions (95) Digital Mental Health Interventions, e-Mental Health and Cyberpsychology (2111) Chatbots and Conversational Agents (740) Generative Language Models Including ChatGPT (708) Anxiety and Stress Disorders (1330) Nursing Communication (29)

Published on in Vol 12 (2025)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/65785, first published .
Comparison of an AI Chatbot With a Nurse Hotline in Reducing Anxiety and Depression Levels in the General Population: Pilot Randomized Controlled Trial

Comparison of an AI Chatbot With a Nurse Hotline in Reducing Anxiety and Depression Levels in the General Population: Pilot Randomized Controlled Trial

Comparison of an AI Chatbot With a Nurse Hotline in Reducing Anxiety and Depression Levels in the General Population: Pilot Randomized Controlled Trial

Authors of this article:

Chen Chen1 Author Orcid Image ;   Kok Tai Lam1 Author Orcid Image ;   Ka Man Yip1 Author Orcid Image ;   Hung Kwan So1 Author Orcid Image ;   Terry Yat Sang Lum2 Author Orcid Image ;   Ian Chi Kei Wong3, 4, 5 Author Orcid Image ;   Jason C Yam6 Author Orcid Image ;   Celine Sze Ling Chui7 Author Orcid Image ;   Patrick Ip1 Author Orcid Image
Article Authors Cited by (6) Tweetations (10) Metrics

Chen Chen   1 , MSc ;   Kok Tai Lam   1 , MPhil ;   Ka Man Yip   1 , MStat ;   Hung Kwan So   1 , PhD ;   Terry Yat Sang Lum   2 , PhD ;   Ian Chi Kei Wong   3, 4, 5 , PhD ;   Jason C Yam   6 , MD ;   Celine Sze Ling Chui   7 , PhD ;   Patrick Ip   1 , MD

1 Department of Paediatrics and Adolescent Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong SAR, China (Hong Kong)

2 Department of Social Work Administration, University of Hong Kong, Hong Kong SAR, China (Hong Kong)

3 Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong SAR, China (Hong Kong)

4 School of Pharmacy, Medical Sciences Division, Macau University of Science and Technology, Macau, China

5 School of Pharmacy, Aston University, Birmingham, United Kingdom

6 Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, Hong Kong SAR, China (Hong Kong)

7 School of Nursing, University of Hong Kong, Hong Kong SAR, China (Hong Kong)

Corresponding Author:

  • Patrick Ip, MD
  • Department of Paediatrics and Adolescent Medicine
  • School of Clinical Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong
  • Room 115, 1/F, New Clinical Building, Queen Mary Hospital, 102 Pokfulam Road
  • Hong Kong SAR
  • China (Hong Kong)
  • Phone: 852 22554090
  • Fax: 852 28551523
  • Email: patricip@hku.hk